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蚂蚁淘在线 / 品牌中心 / Absolute Antibody / absoluteantibody/Ab00534-10.6 Anti-EGFR [Matuzumab]/Ab00534-10.6/ 100 µg
商品描述
Description:RecombinantmonoclonalantibodytoEGFR.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthetherapeuticantibodyMatuzumab.ThisisaFabfragmentwithahis-tag.
SpeciesandIsotype:HumanFabfragment,His-Tagged,kappa
CloneNumber:Matuzumab
UniProtAccessionNumberofTargetProtein:P00533
AlternativeName(s)ofTarget:EpidermalGrowthFactorReceptor
PublishedApplication(s):Block;FC;WB
PublishedSpeciesReactivity:Human
Immunogen:DomainIIIoftheextracellulardomainofhumanEGRF.
Specificity:BindstohumanEGFR.
ApplicationNotes:ThisantibodybindstohumanEGFRatasidedistinctfrmtheantigenbindingsite,preventingconformationalre-arrangementrequiredfordimerization,aprocessessentialforhigh-affinitiyligandbinding(Schmiedel2008).
AntibodyFirstPublishedin:
Murthyetal.BindingofanantagoNISTicmonoclonalantibodytoanintactandfragmentedEGF-receptorpolypeptide.ArchBiochemBiophys.1987Feb1;252(2):549-60.PMID:2434025Noteonpublication:DescribesthegenerationoftheparentalmurineantibodymAb425againsthumanA431carcinomacellsanditsactiononhumanEGFR.
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals. Absolute Antibody我们现在与Digital Proteomics合作提供多克隆永生化服务。这意味着您可以生产可复制且不受限制的多克隆试剂，或者利用天然免疫系统来识别新的抗体候选物。对于这项服务，您可以提供免疫宿主生物的血清和B细胞，纯化的抗原用于免疫，或者只是告诉我们您的靶标，我们将做剩下的事情。鉴于其中之一，我们可以提供多达10条由发现引擎选择的重链序列和10条轻链序列，在交互式报告中提供具有蛋白质组学证据的扩展库，根据要求将抗体工程化为任何种类和同种型，以及我们提供的抗体表征数据获得。此服务是100％免版税的。 SpeciesandIsotype:HumanFabfragment,His-Tagged,kappa
CloneNumber:Matuzumab
UniProtAccessionNumberofTargetProtein:P00533
AlternativeName(s)ofTarget:EpidermalGrowthFactorReceptor
PublishedApplication(s):Block;FC;WB
PublishedSpeciesReactivity:Human
Immunogen:DomainIIIoftheextracellulardomainofhumanEGRF.
Specificity:BindstohumanEGFR.
ApplicationNotes:ThisantibodybindstohumanEGFRatasidedistinctfrmtheantigenbindingsite,preventingconformationalre-arrangementrequiredfordimerization,aprocessessentialforhigh-affinitiyligandbinding(Schmiedel2008).
AntibodyFirstPublishedin:
Murthyetal.BindingofanantagoNISTicmonoclonalantibodytoanintactandfragmentedEGF-receptorpolypeptide.ArchBiochemBiophys.1987Feb1;252(2):549-60.PMID:2434025Noteonpublication:DescribesthegenerationoftheparentalmurineantibodymAb425againsthumanA431carcinomacellsanditsactiononhumanEGFR.
ProductForm
Purification:PurifiedbyImmobilizedMetalAffinityChromatographySuppliedin:PBSonly.
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°CConcentration:Seeviallabel.
