- 关注表位标记
- Primary Antibodies
- Recombinant Antibodies from Human Patients
- Anti-Allergen Antibodies
- 多标签控制蛋白
- Recombinant Isotype Controls
- 抗过敏原抗体
- 重组F4/80克隆CI:A3-1
- 体内研究用重组抗体
- Recombinant F4/80 Clone CI:A3-1
- Research-Grade Biosimilars
- 关注来自人类患者的重组抗体
- 同型对照
- 重组免疫球蛋白Fc结构域（Ig-Fc结构域）
- 人源性重组抗体
- 研究级生物仿制药
- 其他产品
- 抗病毒抗体
- 重组自由轻链
- Antibodies to Epitope Tags
- Anti-Virus Antibodies
UniProtAccessionNumberofTargetProtein:P67875
AlternativeName(s)ofTarget:Aspf1;Aspf1;ribotoxinAspf1;ribonucleasemitogillin;allergenAspfI;AspfI;IgE-bindingribotoxin;majorallergenAspf1;allergen:Aspf1Immunogen:14H4antibodywasraisedusinganoveltechnique:mononuclearcellsweretakenfromthehumansubjectswithallergicbronchopulmonaryaspergillosisandthenscreenedforIgEsecretion.Subsequently,theywereusedtogeneratehybridomasofwhichsomeweresecretinganti-Aspf1IgE.
Specificity:ThisantibodyrecognisesAspf1.
ApplicationNotes:Thisantibody"stargetprotein(Aspf1)wasconfirmedthroughIPandmassspectrometryanalysis(Wurthetal.,2018).WBandELISA:theantibodywassuccessfullindetectingAspf1antigeninacommercialAspergillusextractALKB(Wurthetal.,2018).
Antibodyfirstpublishedin:Wurthetal.HumanIgEmAbsdefinevariABIlityincommercialAspergillusextractallergencompositionJCIInsight.2018Oct18;3(20).pii:123387.doi:10.1172/jci.insight.123387.PMID:30333320Noteonpublication:ThearticledescribesamethodofgeneratingAspergillus-reactiveIgE–secretinghumanhybridomas(amongthemthesesecretingthisantibody).Subsequently,theantibodyischaracterizedanditsspecificityisdetermined.Finally,thisantibodyisusedtodeterminapotentialpresenceofitsantigeninthecommercialy-availableAspergillussamplesusedindiagnosisandtreatmentofAspergillus-relatedallergies.
