Species: Mouse Host Species: HEK293 MW: 45 kDa Genbank #: NM_008798 Tag(s): C-terminal Fc fusion (Mouse IgG2a), C-terminal Avi-tag™ a.a: 25-167 Description:Mouse secreted Programmed Cell Death 1(PD-1)-Fc fusion protein, also known asCD279, PDCD1, and SLEB2, GenBankAccession No. NM_008798, a.a. 25-167,fused at the C-terminus to the Fc portion ofmouse IgG2a and with a C-terminal Avi-tag,expressed in a HEK293 cell expressionsystem. This protein was biotinylated usingAviTagTM technology. MW = 45 kDa. Note:this protein runs at an apparent highermolecular weight due to glycosylation. UniProt Q02242 Synonym(s): Programmed Cell Death 1, CD279, PDCD1, SLEB2 Formulation: 8 mM phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20%glycerol Format: Aqueous buffer solution Storage / Stability: At least 6 months at –80°C. Application(s): Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies. Reference(s):

1. Agata, Y., et al., Internat. Immunol. 1996; 8(5): 765-772.

2. Freeman, G.J. et al., J. Exp. Med. 2000; 192(7): 1027-1034.

Notes:

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Warning(s): Avoid freeze/thaw cycles. Protein may be diluted to
≥ 100 μg/ml in PBS + glycerol and stored at -80°C. Scientific Category: Immunotherapy Product Type: Fc Fusion Protein Data shown is lot-specific. Contact us for specific information on other lots.

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