Background:Bromodomains function as acetyl-lysine binding domains, and bromodomain/ acetyl-lysine recognition can regulate histone modification, DNA replications, chromatin remodeling, and gene transcription. Description:The Bromodomain Ligand 2 isa peptide derived from histone H3 that includes an acetylated lysine. It contains a C-terminal GG linker, followed by a biotinylated Lys. This peptide is suitable for use as a ligand for several bromodomains including BAZ2B. Purity: ≥95% Supplied As: 20 µM aqueous solution Concentration: 20 µM Format: Aqueous buffer solution Storage / Stability:

At least 6 months from date of receipt, when stored as directed

Application(s): Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling. Reference(s): Muller, S., et al. Expert Rev. Mol. Med. 2011 Sep 13;13:e29. Warning(s): Avoid freeze/thaw cycles. Scientific Category: Bromodomain Product Type: Substrate Data shown is lot-specific. Contact us for specific information on other lots.

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