Species: Mouse Host Species: HEK293 MW: 51.8 kDa Genbank #: NM_021893 Tag(s): C-terminal Fc fusion (Mouse IgG2a) a.a: 19-238 Description:Mouse secreted Programmed Cell Death 1Ligand 1 (PD-L1)-Fc fusion protein, alsoknown as CD274 and B7 homolog 1 (B7-H1), GenBank Accession No. NM_021893,a.a. 19-238, fused at the C-terminus to theFc portion of mouse IgG2a, expressed in aHEK293 cell expression system. MW = 51.8kDa. UniProt Q9EP73 Synonym(s): Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7-H1) Formulation: 8 mM phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20%glycerol. Format: Aqueous buffer solution Storage / Stability: At least 6 months at –80°C. Application(s): Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies. Reference(s):

1. Freeman, G.J., et al., J. Exp. Med. 2000; 192(7):1027-34. 2. Dong, H., et al., Nat. Med. 1999; 5(12):1365-9.

Product Specific Reference(s):1. Lmai, Y., et al., J. Immunol. 2015; 195(2): 421-425.

Notes:

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Warning(s): Avoidfreeze/thaw cycles. Storing diluted protein isnot recommended, if necessary, use carrierprotein (BSA 0.1 – 0.5%). Scientific Category: Immunotherapy Product Type: Recombinant protein Data shown is lot-specific. Contact us for specific information on other lots.

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