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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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商品描述
Background:
CD39contributestoimmuneregulationthroughthehydrolysisofATPtoAMPintheratelimitingstepofextracellularadenosineproduction.CD39isexpressedonthesurfaceofmultiplecellsoftheimmunesystemincludingT-cells,Naturalkillercells,B-cells,dendriticcellsandmacrophages.Inaddition,highlevelsofCD39expressionhavebeenassociatedwiththetumormicroenvironment(TME).ResearchaimedatreducingimmunosuppressionbyCD39activityhasresultedinthestudyofasmallmoleculeinhibitor,POM1,andmultipleanti-CD39antibodiesselectedforblockingenzymaticactivity ordecreasingCD39expression.

Description:
The5XCD73AssayBufferisoptimizedforassayingCD73.ThisbufferisdesignedforBPSBioscience"scolorimetricassays(cat#72055andcat#72058).
SuppliedAs:
Tris-bufferedsolution
Format:
Aqueousbuffersolution
Storage/StABIlity:
-80°C.Avoidfreeze/thawcycles.Atleast12monthsfromdateofreceipt,whenstoredasdirected.
Application(s):
Suitableforstudyingenzymekinetics,andscreeningsmallmolecularinhibitorsofCD73forHTSapplicationsindrugdiscovery.
ScientificCategory:
Immunotherapy
ProductType:
AssayKitComponent
Datashownislot-specific.Contactusforspecificinformationonotherlots.


