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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Overview
Epidermalgrowthfactor(EGF)ischaracterizedbyhighaffinitybindingtovariousEGFreceptors(EGFRs)andtheproductionofmitogenicresponses(Carpenter&Cohen).EGFpromotesEGFRdimerization,resultinginactivationofdownstreampathwaysincludingPI3K,ERK1/2,JAK/STAT,β-catenin,andcalciumsignaling.EGFissecretedbythegut-associatedsalivaryandBrunner’sglands,isfoundinavarietyofbodyfluids,andstimulatescellproliferationanddifferentiationinrodentandneonatalhumanintestine(Wrightetal.).CentralnervoussystemstemcellsalsoproliferateinresponsetotheEGFstimulus(Reynolds&Weiss).
AlternativeNames:
Beta-urogastrone,HOMG4,Epidermalgrowthfactor,Pro-epidermalgrowthfactor,URG,Urogastrone
CellType:
MesenchymalStemandProgenitorCells;ProstateCells;PluripotentStemCells;Neurons;NeuralStemandProgenitorCells;BrainTumorStemCells;HematopoieticStemandProgenitorCells;NeuralCells,PSC-Derived;Endoderm,PSC-Derived;Mesoderm,PSC-Derived
Species:
Human
AreaofInterest:
StemCellBIOLOGy;Neuroscience;EpithelialCellBiology
MolecularWeight:
6.2kDa
Purity:
>95%
