商品描述
Product name1205 Lu Viable CellsCatalog number1205 Lu-01-0001-A (1ml)Description1205Lu is a metastatic human melanoma cell line established from a metastatic site (lung) in a 37 year-old male patient. 1205Lu cells produce xenograft tumors when injected into immunocompromised mice. This cell line features a BRAF V600E mutation as well as hemizygous deleted PTEN and CDK4 K22Q mutation. Cyclin-dependent kinase 4 (CDK4) is a gene that encodes a serine/threonine kinase. The protein functions in cell cycle progression from G1 to S phase and the activation of RB1. Missense and silent mutations are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.This cell line is wild type for N-ras and c-KIT.Price for Non-Profit Organisation Only. Item subject to MTA. SourceRocklandProduct categoryCells, Media & FractionsProduct sub categoryCell LinesTarget speciesHumanShipment infoDry IceNacres CodificationNA.81 Tebu-Bio通过我们广泛的完全可定制的服务,在体外模拟人体的生理环境。您指定的项目经理将帮助您定义最佳方法,以建立概念验证,发现和了解NCE和生物制剂的作用机理,获取具有相关生物标志物的证据...我们可以根据您不断变化的需求来处理您的全部或部分项目。所有CRO工作都是在我们通过ISO9001:2015和ISO14001:2015欧洲认证的实验室中秘密进行的,并且有明确但灵活的截止日期。无论您的研究领域是什么,通过外包到tebu-bio,您都可以节省时间和成本,同时确保您完全控制研究和知识产权。