商品描述
Product name451Lu Non-Viable Cell Pellet (10 x 10^6 cells)Catalog number451Lu-03-0010-A (10mg)DescriptionBackground : Non-viable cell pellet was generated from cell line 451Lu. 451Lu is a selected xenograft aggressive metastatic sub-line of WM164. WM164 is a metastatic human melanoma cell line established from a metastatic site (right upper arm) in a 22-year-old male with stage IV superficial spreading melanoma. 451Lu cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line is wild type for PTEN, N-RAS, c-KIT, and CDK4 genes.Application Note : Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. SourceRocklandProduct categoryCells, Media & FractionsProduct sub categoryCell Lysates & RNATarget speciesHumanShipment infoDry IceNacres CodificationNA.61 Tebu-Bio通过我们广泛的完全可定制的服务，在体外模拟人体的生理环境。您指定的项目经理将帮助您定义最佳方法，以建立概念验证，发现和了解NCE和生物制剂的作用机理，获取具有相关生物标志物的证据...我们可以根据您不断变化的需求来处理您的全部或部分项目。所有CRO工作都是在我们通过ISO9001：2015和ISO14001：2015欧洲认证的实验室中秘密进行的，并且有明确但灵活的截止日期。无论您的研究领域是什么，通过外包到tebu-bio，您都可以节省时间和成本，同时确保您完全控制研究和知识产权。
