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商品描述
ProductDescription
CatalogueNumber: | AN00001 |
ProductName: | anti-14-3-3antibody |
Form: | liquid |
Host: | Rabbit |
Clonity: | polyclonal |
Isotope: | IgG |
Storage: | PBSwith0.02%sodiumazideand50%glycerolpH7.3,-20â&BDquo;ƒfor24months(Avoidrepeatedfreeze/thawcycles.) |
Background: | 14-3-3theta(alsoknownasYWHAQ,or14-3-3tau)isamemberof14-3-3proteinswhichwerethefirstphosphoserine/phosphothreonine-bindingproteinstobediscovered.14-3-3familymembersinteractwithawidespectrumofproteinsandpossessdiversefunctions.Mammalsexpresssevendistinct14-3-3isoforms(gamma,epsilon,beta,zeta,sigma,theta,tau)thatformmultiplehomo-andhetero-dimmers.14-3-3proteinsdisplaythehighestexpressionlevelsinthebrain,andhavebeenimplicatedinseveralneurodegenerativediseases,includingAlzheimer"sdiseaseandamyotrophiclateralsclerosis.Thisantibodywasraisedagainstfull-length14-3-3theta. |
Immunogen: | tyrosine3-monooxygenase/tryptophan5-monooxygenaseactivationprotein,thetapolypeptide |
Synonyms: | 14-3-3proteintheta |
CalculatedMW: | 28kDa |
Specificity: | Human,Mouse,Rat |
TestedApplication: | ELISA,IF,IP,IHC,WB |
RecommendedDilution: | WB:1:1000-1:10000;IP:1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200 |
IHCDilution: | Immunohistochemistryofparaffin-embeddedmousebraintissueslideusing14-3-3Antibodyatdilutionof1:50 |
WBDilution: | HelacellweresubjectedtoSDSPAGEfollowedbywesternblotwith14-3-3Antibodyatdilutionof1:3000 |