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商品描述
ProductDescription
CatalogueNumber: | AN00002 |
ProductName: | anti-14-3-3antibody |
Form: | liquid |
Host: | Mouse |
Clonity: | monoclonal |
Isotope: | IgG1 |
Storage: | PBSwith0.02%sodiumazideand50%glycerolpH7.3,-20â&BDquo;ƒfor24months(Avoidrepeatedfreeze/thawcycles.) |
Background: | 14-3-3theta(alsoknownasYWHAQ,or14-3-3tau)isamemberof14-3-3proteinswhichwerethefirstphosphoserine/phosphothreonine-bindingproteinstobediscovered.14-3-3familymembersinteractwithawidespectrumofproteinsandpossessdiversefunctions.Mammalsexpresssevendistinct14-3-3isoforms(gamma,epsilon,beta,zeta,sigma,theta,tau)thatformmultiplehomo-andhetero-dimmers.14-3-3proteinsdisplaythehighestexpressionlevelsinthebrain,andhavebeenimplicatedinseveralneurodegenerativediseases,includingAlzheimer"sdiseaseandamyotrophiclateralsclerosis.Thisantibodywasraisedagainstfull-length14-3-3theta. |
Immunogen: | tyrosine3-monooxygenase/tryptophan5-monooxygenaseactivationprotein,thetapolypeptide |
Synonyms: | 14-3-3proteintheta |
CalculatedMW: | 28kDa |
Specificity: | Human,Rat |
TestedApplication: | ELISA,WB,IHC,IF |
RecommendedDilution: | WB:1:500-1:5000;IHC:1:20-1:200;IF:1:20-1:200 |
IHCDilution: | Immunohistochemistryofparaffin-embeddedratbraintissueslideusing14-3-3Antibodyatdilutionof1:50 |
WBDilution: | humanbraintissueweresubjectedtoSDSPAGEfollowedbywesternblotwith14-3-3antibodyatdilutionof1:1000 |