Therearetwotypesoflightchaininmammals,thekappachain;encodedbytheimmunoglobulinkappalocusonchromosome2,andthelamBDachain;encodedbytheimmunoglobulinlambdalocusonchromosome22.AntibodiesareproducedbyBlymphocytes,eachexpressingonlyoneclassoflightchain.Onceset,lightchainclassremainsfixedforthelifeoftheBlymphocyte.

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