- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
PKCαisamemberoftheproteinkinaseC(PKC)familyofserine-andthreonine-specificproteinkinasesthatcanbeactivatedbycalciumandthesecondmessengerdiacylglycerol.PKC-alphahasbeenreportedtoplayrolesinmanydifferentcellularprocesses,suchascelladhesion,celltransformation,cellcyclecheckpoint,andcellvolumecontrol(1).PKCαhasbeenassignedtothechromosomeregion17q22-q23.2andhasbeenidentifiedasafundamentalregulatorofcardiaccontractilityandCa(2+)handlinginmyocytes(2).
GeneAliases:
PRKCA;MGC82897
GenbankNumber:
BC078065
References:
1.Coussens,L.etal:Multiple,distinctformsofbovineandhumanproteinkinaseCsuggestdiversityincellularsignalingpathways.Science233:859-866,1986.2.Braz,JC.etal:PKC-alpharegulatescardiaccontractilityandpropensitytowardheartfailure.NatureMed.10:248-254,2004.
