品牌分类
- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Overview:
PotentandselectiveinhibitorofjumonjiH3K27histonedemethylasesJMJD3andUTX(IC50=60nM,humanJMJD3).ThisisthefirstknowninhibitorselectivefortheH3K27me3-specificJMJsubfamilywhichbindstotheactivecatalyticsiteoftheenzyme.TheCOOHgroupconferscellimpermeABIlityandassuchisusefulasastandardininvitroassays.Acellpermeableethylesteranalogisalsoavailable.
References:
1.LKruidenieretal.Nature2012488:404
