- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
CDC25C(alsoknownascelldivisioncycle25homologC)isamemberoftheCDC25phosphatasefamily.CDC25Cishighlyconservedduringevolutionanditplaysakeyroleintheregulationofcelldivision.CDC25Cactivatesthepartiallypurifiedp34(cdc2)/cyclinBcomplexanddirectsthedephosphorylationofcyclinB-boundCDC2andtriggersentryintomitosis(1).CDC25Calsosuppressesp53-inducedgrowtharrest.TheregulationofCDC25Bphosphorylationbyp38isacriticaleventforinitiatingtheG2/McheckpointafterultravioletrADIation(2).
GeneAliases:
CDC25
GenbankNumber:
BC019089
References:
1.Gould,K.L.et.al:Complementationofthemitoticactivator,p80(cdc25),byahumanprotein-tyrosinephosphatase.Science250:1573-1576,1990.2.Bulavin,D.V.et.al:InitiationofaG2/Mcheckpointafterultravioletradiationrequiresp38kinase.Nature411:102-107,2001.