- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
ULK4, or Unc-51-like kinase 4, is a Ser/Thr protein kinase that is a member of the APG1/unc-51/ULK1 subfamily. ULK4 contains five HEAT repeats and a catalytic kinase domain. The ULK4 gene is conserved in many species including chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, and rice (1). ULK4 has been implicated as a gene involved in the development of hydrocephalus (2). This neurologic disorder in animal models is being used to elucidate factors responsible for the excessive accumulation of cerebrospinal fluid in hydrocephalic humans.
Gene Aliases:
DKFZp434E1822; FAM7C1; FLJ20574; REC01035
Genbank Number:
NM_017886
References:
1. Krupnova T et al: Microtubule-associated kinase-like protein RUNKEL needed [corrected] for cell plate expansion in Arabidopsis cytokinesis. Curr Biol. 2009 Mar 24;19(6):518-23. 2. Vogel, P. et al: Congenital Hydrocephalus in Genetically Engineered Mice. Vet Pathol. 2011 Jul 11.