- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
Tau-316encodesthemicrotubule-associatedproteintau(MAPT)whosetranscriptundergoescomplex,regulatedalternativesplicing,givingrisetoseveralmRNAspecies.Tau-316transcriptsaredifferentiallyexpressedinthenervoussystem,dependingonstageofneuronalmaturationandneurontype(1).Tau-316genemutationshavebeenassociatedwithseveralneurodegenerativedisorderssuchasAlzheimer"sdisease,Pick"sdisease,frontotemporaldementia,cortico-basaldegenerationandprogressivesupranuclearpalsy(2).
GeneAliases:
Fetal-tau,Tau-A,TAU;MAPT,MSTD;PPND;DDPAC;MAPTL;MTBT1;MTBT2;FTDP-17
GenbankNumber:
P10636-3
References:
1.Brown,J.et.al:Familialdementiawithswollenachromaticneuronsandcorticobasalinclusionbodies:aclinicalandpathologicalstudy.J.Neurol.Sci.135:21-30,1996.2.Alonso,A.D.C.et.al:Alzheimer"sdiseasehyperphosphorylatedtausequestersnormaltauintotanglesoffilamentsanddisassemblesmicrotubules.NatureMed.2:783-787,1996.
