品牌分类
- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Overview:
HTRA4 is a serine protease with a conserved trypsin domain and a PDZ domain.As other related family members, HTRA4 may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. HrtA4 may contribute to shallow trophoblast invasion in preeclampsia (1) and imply a potential application as a biomarker for this disorder (2).
Gene Aliases:
None
Genbank Number:
NM_153692
References:
1.Wang LJ. et.al:High-temperature requirement protein A4 (HtrA4) suppresses the fusogenic activity of syncytin-1 and promotes trophoblast invasion. Mol Cell Biol. 2012 Sep;32(18):3707-17. 2.Inagaki A. et.al:Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia. Placenta. 2012 Nov;33(11):919-26.
