- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
STK19isamemberoftheserine/threoninekinasefamilythatshowsamanganese-dependentproteinkinaseactivityandphosphorylatesα-caseinatser/thrresiduesandhistoneatserresidues.STK19containsapositivelychargedputativenuclearlocalizationsignal,multiplepotentialphosphorylationsites,2amidationsites,9potentialN-myristoylationsites,andnoN-glycosylationsites.STK19hasbeenshowntolocalizepredominantlyinthenucleus(1).ThephosphorylationofSTK19isthoughttobeinvolvedintranscriptionalregulation.STK19localizestothemajorhistocompatibilitycomplex(MHC)classIIIregiononchromosome6(2).
GeneAliases:
D6S60;D6S60E;G11;HLA-RP1;RP1
GenbankNumber:
NM_004197
References:
1.Gomez-Escobar,N.et.al:TheG11genelocatedinthemajorhistocompatibilitycomplexencodesanovelnuclearserine/threonineproteinkinase.J.Biol.Chem.273:30954-30960,1998.2.Shen,L.et.al:StructureandgeneticsofthepartiallyduplicatedgeneRPlocatedimmediatelyupstreamofthecomplementC4AandtheC4BgenesintheHLAclassIIIregion:molecularcloning,exon-intronstructure,compositeretroposon,andbreakpointgeneduplication.J.Biol.Chem.269:8466-8476,1994.
