- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
NDR2orNuclearDbf2-relatedproteinisaserine/threoninekinaseinthesubgroupoftheAGCkinasefamily.NDR2isregulatedbyMobproteinsandisalsoknownasserine/threoninekinase38like(STK38L)(1).NDR2actasnovelpro-apoptotickinasethatisactivatedbyRASSF1A/MST1inresponsetoFasreceptorstimulationandpromotesapoptosis(2).NDR2ismainlyinvolvedintheregulationofstructuralprocessesindifferentiatingandmatureneuronalcellsanditishighlyexpressedwithhighestlevelsobservedinthethymus(3).
GeneAliases:
KIAA0965;STK38L
GenbankNumber:
NM_015000
References:
1.Millward,T.et.al:Molecularcloningandcharacterizationofaconservednuclearserine(threonine)proteinkinase.Proc.Nat.Acad.Sci.92:5022-5026,1995.2.VichalkovskiA.et.al:NDRkinaseisactivatedbyRASSF1A/MST1inresponsetoFasreceptorstimulationandpromotesapoptosis.CurrBiol.2008Dec9;18(23):1889-95.3.DevroeE.et.al:HumanMobproteinsregulatetheNDR1andNDR2serine-threoninekinases.J.Biol.Chem.279:24444-24451,2004.