- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
SCFisastromalcell-derivedcytokinesynthesizedbyfibroblastsandothercelltypes.SCFpromotesproliferationandearlydifferentiationofcellsatthelevelofmultipotentstemcells.IthasbeensuggestedthatSCFisessentialforoptimalproductionofvarioushematopoieticlineages,mainlybecauseofitsABIlitytopreventapoptosiswhenco-stimulatedwithothercytokines.ThereceptorforSCF,designatedSCFR(CD117)istheoncogenedesignatedasKIT.TheBIOLOGicalactivitiesofSCFareconsiderablysynergisedbycolonystimulatingfactors;GM-CSFandG-CSF,andbyIL7,EPOandsomeothergrowthanddifferentiationfactors.IncombinationwithIL7,SCFstimulatestheproliferationofpre-Bcells.SCFisalsoapotentchemoattractantforcellsexpressingthekitreceptor.RecombinantHumanSCFisamonomericproteinthatcontainsintra-chaindisulfidebonds.
GenbankNumber:
P21583
