品牌分类
- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
蚂蚁淘在线 / 品牌中心 / Signalchem / Signalchem/Anti-phospho-STK10-a (Ser482 Ser486 Ser490)/100 ul/S29-165R-100
商品描述
Overview:
Polo-likekinase(PLK)playsanimportantroleincellcycleregulation.PLKisalsorequiredforbipolarspindleformation,activationoftheanaphase-promotingcomplex/cyclosome,andcytokinesis.DeregulationofPLKsoftenresultsinabnormalitiesincentrosomeduplication,maturationand/ormicrotubuledynamics(1).STK10-a,whichisalsoknownasPLKKislikelyresponsIBLeforactivatingPLK.STK10-aitselfisactivatedbyphosphorylationatSer482,Ser486andSer490(2).
References:
1.Nigg,EA.etal:Dynamicchangesinnucleararchitectureduringmitosis:ontheroleofproteinphosphorylationinspindleassemblyandchromosomesegregation.ExpCellRes.1996Dec15;2292.EriksonEetal.Afeedbackloopinthepolo-likekinaseactivationpathway.JBiolChem.2004,279:32219-32224.
