References:

1. Li G, et al: Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules. J Biol Chem. 2004 Apr 16;279(16):15938-45. 2. Noble W, et al: Cdk5 is a key factor in tau aggregation and tangle formation in vivo. Neuron. 2003 May 22;38(4):555-65. 3. Giasson BI, et al: The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry. 2002 Dec 24;41(51):15376-87. 4. Lee G, et al: The microtubule binding domain of tau protein. Neuron. 1989 Jun;2(6):1615-24.5. Andreadis A et al: Structure and novel exons of the human tau gene. Biochemistry. 1992 Nov 3;31(43):10626-33.