Additional Information	CHO derived
Details of Functionality	Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50 for this effect is 0.2‑1.2ng/mL.The specific activity of Recombinant Human/Mouse/Rat Activin A is approximately 1 IU/μg, which is calibrated against human ActivinA WHOInternational Standard (NIBSC code: 91/626).
Source	Chinese Hamster Ovary cell line, CHO-derived Activin A proteinGly311-Ser426
Accession #	P08476
N-terminal Sequence	Gly311
Structure / Form	Disulfide-linked homodimer
Protein/Peptide Type	Recombinant Proteins
Gene	INHBA
Purity	>95%, by SDS-PAGE with silver staining.
Endotoxin Note	<0.01 eu="" per="" 1="" μg="" of="" the="" protein="" by="" the="" lal="">

Theoretical MW	13 kDa (monomer). Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
SDS-PAGE	14 kDa, reducing conditions24 kDa, non-reducing conditions
Publications	ReadPublications using 338-AC in the following applications: Bioassay 317 publications Cell Culture 22 publications Differentiation 4 publications ELISA (Standard) 1 publication Flow Cytometry 1 publication In Vivo 6 publications Stimulation 1 publication Surface Plasmon Resonance 2 publications

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