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商品描述
| Kitsize | 12x8 |
| Method | LuminescenceImmunoassay |
| Incubationtime | 1x4h,1x10min |
| Standardrange | 6.4-760pg/mL |
| Specimen/Volumes | 50µLsaliva/withoutextraction |
| Substrate/isotope | Acridiumbased |
| RegulatoryStatus: | EU:CE,CDN:IVD |
Detailsfor:TestosteroneLuminescenceImmunoassay
IBL我们的液体处理专业知识可实现高度复杂的分子诊断技术的可靠自动化，例如细胞遗传学（核型分析和FISH）和分子细胞遗传学（aCGH /阵列比较基因组杂交），其应用范围从代谢疾病和癌症到生殖遗传学和移植药物。该产品组合涵盖了细胞遗传学和分子细胞遗传学工作流程的关键阶段，从标准化工作站，经过验证的应用程序和专用用户界面，到与Tecan Labwerx合作开发的高度定制的平台。 LuminescenceImmunoassayforthequantitativedeterminationoffreetestosteroneinsalivaandoftotaltestosteroneindilutedserum.Measurementoftestosterone(amalesexhormone)isusedinthediagnosisandtreatmentofdisordersinvolvingthemalesexhormones(androgens),includingprimaryandsecondaryhypogonADIsm,impotenceinmalesandinfemaleshirsutism(excessivehair)andvirilization(masculinization)duetotumors,polycysticovariesandadrenogenitalsyndromes.
Testosterone,aC19-Steroid,isthemosteffectivenaturalhormoneinthefamilyofandrogens.Inmales,itismainlyproducedintheLeydigcellsofthetestes,onlyasmallamountisproducedintheadrenalcortex.Onthewhole,adultmaleshave10to20foldhighertestosteroneplasmaconcentrationsthanfemales.
Inthecirculation,themainpartoftestosteroneisboundtoplasmaproteinslikesexhormonebindingglobuline(SHBG)andalbumine.Only1–2%ofthetestosteroneisunboundandthereforeBIOLOGicallyactive.
Thefreetestosteroneisreleasedviathesalivaryglands.Intheircellsagreatpartofthehormoneistransformedto5a-Dihydrotestosterone.Nevertheless,theconcentrationoftestosteroneinsalivareflectstheleveloffreetestosteroneinplasma.
Testosteronelevelsinfemalesshouldbemeasuredinpatientshavingclinicalsymptomsofvirilismcausedbytheadrenogenitalsyndrome,thepolycysticovarysyndromeorneoplasmsoftheadrenalcortexortheovaries.Duetothefluctuations,repeatedmeasurementsarerecommended.Atherapywithandrogensuppressivedrugscanbefollowedupbytakingcontrols.
Inmenwithsignsofprimaryorsecondaryhypogonadism,confirmatorytestosteronelevelscanbedetermined.
Testosteronetogetherwithcortisollevelsinstressresearchandsportsmedicinerepresentsausefulparameter.Duetothemanyfactorsthatmayinfluencethetestosteronelevels,itisinsomesituationsadvisabletotakeaprofile.Thereforemeasuringthefreetestosteroneinsalivaisaconvenientmethod,duetotheeasiersamplecollectionwithoutrepeatedvenipunctures.
Ifyouneedmoredetailedinformationpleasevisitourwebpage
www.saliva-diagnostics.com.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Testosterone,aC19-Steroid,isthemosteffectivenaturalhormoneinthefamilyofandrogens.Inmales,itismainlyproducedintheLeydigcellsofthetestes,onlyasmallamountisproducedintheadrenalcortex.Onthewhole,adultmaleshave10to20foldhighertestosteroneplasmaconcentrationsthanfemales.
Inthecirculation,themainpartoftestosteroneisboundtoplasmaproteinslikesexhormonebindingglobuline(SHBG)andalbumine.Only1–2%ofthetestosteroneisunboundandthereforeBIOLOGicallyactive.
Thefreetestosteroneisreleasedviathesalivaryglands.Intheircellsagreatpartofthehormoneistransformedto5a-Dihydrotestosterone.Nevertheless,theconcentrationoftestosteroneinsalivareflectstheleveloffreetestosteroneinplasma.
Testosteronelevelsinfemalesshouldbemeasuredinpatientshavingclinicalsymptomsofvirilismcausedbytheadrenogenitalsyndrome,thepolycysticovarysyndromeorneoplasmsoftheadrenalcortexortheovaries.Duetothefluctuations,repeatedmeasurementsarerecommended.Atherapywithandrogensuppressivedrugscanbefollowedupbytakingcontrols.
Inmenwithsignsofprimaryorsecondaryhypogonadism,confirmatorytestosteronelevelscanbedetermined.
Testosteronetogetherwithcortisollevelsinstressresearchandsportsmedicinerepresentsausefulparameter.Duetothemanyfactorsthatmayinfluencethetestosteronelevels,itisinsomesituationsadvisabletotakeaprofile.Thereforemeasuringthefreetestosteroneinsalivaisaconvenientmethod,duetotheeasiersamplecollectionwithoutrepeatedvenipunctures.
Ifyouneedmoredetailedinformationpleasevisitourwebpage
www.saliva-diagnostics.com.
