Product ID A4924Cas No. 1002304-34-8Purity ≥98%

• Description
• Product Info
• Shipping and Storage
• Downloads
• References

Description

AMG-208 is an inhibitor of c-MET and Ron that exhibits anticancer chemotherapeutic activity in prostate cancer models in vitro and in vivo.

Product Info

Cas No.PurityFormulaFormula Wt.IUPAC NameSynonymAppearance

1002304-34-8

≥98%

C22H17N5O2

383.40

7-methoxy-4-[(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline

AMG208

White to off white powder

Shipping and Storage

Store TempShip Temp

-20°C

Ambient

Downloads

Info Sheet

A4924 Info Sheet PDF

References

Liu X, Newton RC, Scherle PA. Developing c-MET pathway inhibitors for cancer therapy: progress and challenges. Trends Mol Med. 2010 Jan;16(1):37-45. PMID: 20031486.

Albrecht BK, Harmange JC, Bauer D, et al. Discovery and optimization of triazolopyridazines as potent and selective inhibitors of the c-Met kinase. J Med Chem. 2008 May 22;51(10):2879-82. PMID: 18426196.

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