Description: Group I/group II mGlu antagonist Chemical Name: (RS)-α-Ethyl-4-carboxyphenylglycine Purity: ≥99% (HPLC) Biological Activity Technical Data Solubility Calculators DatasheetsReferences

Biological Activity

Novel group I/group II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG (Cat. No. 0336).

Technical Data

M. Wt	223.23
Formula	C11H13NO4
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	170846-89-6
PubChem ID	3937355
InChI Key	AIEFWRHRHFRLFT-UHFFFAOYSA-N
Smiles	NC(C(O)=O)(CC)C1=CC=C(C(O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility

Soluble to 100 mM in 1.1eq. NaOH

Preparing Stock Solutions

The following data is based on the product molecular weight 223.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg

1 mM	4.48 mL	22.4 mL	44.8 mL
5 mM	0.9 mL	4.48 mL	8.96 mL
10 mM	0.45 mL	2.24 mL	4.48 mL
50 mM	0.09 mL	0.45 mL	0.9 mL

Molarity Calculator

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution. Reconstitution Calculator

Reconstitution Calculator

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis / Product Datasheet Safety Datasheet Select another language: English German French Spanish View SDS

References

References are publications that support the products\' biological activity.

Bedingfield et al (1995) Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). Br.J.Pharmacol. 116 3323 PMID: 8719814

Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745

---

Keywords: E4CPG, supplier, Group, II, group, I, mGlur, antagonists, Receptors, mGlu2, mGlu3, mGluR2, mGluR3, Glutamate, Metabotropic, mGlu1, mGlu5, mGluR1, mGluR5, Glutamate, (Metabotropic), Group, I, Receptors, Glutamate, (Metabotropic), Group, II, Receptors, Glutamate, (Metabotropic), Group, I, Receptors, Tocris Bioscience

>>> 更多资讯详情请访问蚂蚁淘商城