细胞色素 P450 (CYP450) 酶是一组多样化的催化剂，在人类中包含 57 个成员。 CYPs 通常是膜结合的并且定位于线粒体内部或内质网状膜。 CYP 具有加氧酶活性。
产品背景基因数据细胞色素 P450 抑制剂Cat. No.产品名称/活性6520醋酸阿比特龙强效CYP17A1抑制剂3388阿那曲唑强效芳香酶（CYP19）抑制剂6170盐酸西那卡塞强效CYP2D2抑制剂；也是 CaSR 变构激动剂和 Ca2+ 通道阻滞剂 4096 克霉唑细胞色素 P450 抑制剂；抗真菌药 6108GaleteroneCYP17 抑制剂；雄激素受体拮抗剂阻断视黄酸代谢3292甲吡酮细胞色素 P450 抑制剂5680Vatalanib succinate强效芳香化酶抑制剂；还有 VEGFR 抑制剂底物猫。编号P产品名称/活性62047-乙氧基试卤灵荧光 CYP450 底物4816戊氧基试卤灵荧光细胞色素 P450 底物相关靶标细胞代谢MitoBrilliant™ 染料加氧酶/氧化酶细胞色素 P450 (CYP450) 酶是一组多样化的催化剂，在人类中包含 57 个成员。 CYPs 通常是膜结合的并且定位于线粒体内部或内质网状膜。 CYP 具有加氧酶活性，通常催化氧化还原反应，涉及底物的氧化和水的还原。这组酶在活性位点内含有血红素铁，它对催化活性至关重要。
CYP 已在所有测试的生物体中发现并普遍表达。它们在肝脏中的含量很高，在肝脏中它们在药物和内源性有毒化合物（例如胆红素）的代谢中起着重要作用。大多数 CYP 可以代谢多种底物，这就是它们在药物相互作用中的主要作用反应。 CYPs 还在类固醇激素合成、胆固醇合成和维生素 D 代谢中发挥作用。
细胞色素 P450 药理学信息的外部来源：BJP 指南细胞色素 P450 基因数据基因物种基因符号基因登录号蛋白质登录号 CYP1A1HumanCYP1A1NM_000499P04798MouseCyp1a1NM_0099 92P00184RatCyp1a1NM_012540P00185CYP1A2HumanCYP1A2NM_000761P05177MouseCyp1a2NM_009993P00186RatCyp1a2NM_012541P04799CYP1B1HumanCYP1B1NM_ 000104Q16678MouseCyp1b1NM_009994Q64429RatCyp1b1NM_012940Q64678CYP2A4MouseCyp2a4NM_009997P15392CYP2A5MouseCyp2a5NM_007812P20852CYP2A6Hu manCYP2A6NM_000762Q9UK48CYP2A7HumanCYP2A7NM_030589P20853CYP2A13HumanCYP2A13NM_000766Q16696CYP2A22MouseCyp2a22NM_001101467NP_001094937CY P2B6HumanCYP2B6NM_000767P20813RatCyp2b6M19973AAA41048CYP2B9MouseCYP2B9NM_010000P12790CYP2B10MouseCyp2b10NM_009999P12791CYP2B13MouseCyp2b1 3NM_007813NP_031839RatCyp2b21NM_198733Q9JJ02CYP2B19MouseCyp2b19NM_007814O55071CYP2C8HumanCYP2C8NM_000770P10632CYP2C9HumanCYP2C9NM_000771P11712CYP2C18HumanCYP2C18NM_000772P33260CYP2C19HumanCYP2C19NM_000769P33261CYP2C29MouseCyp2c29NM_007815Q64458CYP2C37MouseCyp2c3 7NM_010001P56654RatCyp2c37XM_001063361XP_001063361CYP2C40MouseCyp2c40NM_010004P56657CYP2C55MouseCyp2c55NM_028089Q9D816CYP2D6HumanCYP2 D6NM_000106P10635RatCyp2d4v1NM_138515P13108CYP2E1HumanCYP2E1NM_000773P05181MouseCyp2e1NM_021282Q05421RatCyp2e1NM_031543Q71UV8CYP2F1 HumanCYP2F1NM_000774P24903CYP2F2MouseCyp2f2NM_007817P33267CYP2J2HumanCYP2J2NM_000775P51589CYP2J6MouseCyp2j6NM_010008O54750CYP2R1HumanCYP2R 1NM_024514Q6VVX0MouseCyp2r1NM_177382Q6VVW9RatCyp2r1NM_001108499XP_341910CYP2S1HumanCYP2S1NM_030622Q96SQ9MouseCyp2s1NM_028775Q9DBX6RatCy p2s1NM_001107495Q66H37CYP2U1HumanCYP2U1NM_183075Q7Z449MouseCyp2u1NM_027816Q9CX98RatCyp2u1NM_001024779Q4V8D1CYP2W1HumanCYP2W1NM_017781 Q8TAV3MouseCyp2w1XM_620268XP_620268RatCyp2w1XM_221971XP_221971CYP3A4HumanCYP3A4NM_017460P08684CYP3A5HumanCYP3A5NM_000777P20815CYP3A7Human CYP3A7NM_000765P24462CYP3A11MouseCyp3a11NM_007818Q64459CYP3A13鼠标Cyp3a13NM_007819Q64464CYP3A16鼠标Cyp3a16NM_007820Q64481CYP3A25鼠标Cyp3a25NM_019792O09158CYP3A41a鼠标Cyp3a41aNM_017396Q9JMA7C YP3A41bMouseCyp3a41bNM_001105159NP_001098629CYP3A43HumanCYP3A43NM_057096Q9HB55CYP3A44MouseCyp3a44NM_177380NP_796354CYP4A10MouseCyp4a10NM_ 010011O88833RatCyp4a10NM_153307NP_695219CYP4A11HumanCYP4A11NM_000778Q02928CYP4A22HumanCYP4A22XM_208213Q5TCH4CYP4B1HumanCYP4B1NM_000779P 13584MouseCyp4b1NM_007823Q64462RatCyp4b1NM_016999P15129CYP4F2HumanCYP4F2NM_001082P78329CYP4F3HumanCYP4F3NM_000896Q08477CYP4F8HumanCYP4F8 NM_007253P98187CYP4F11HumanCYP4F11NM_021187Q9HBI6CYP4F12HumanCYP4F12NM_023944Q9HCS2CYP4F13MouseCyp4f13NM_130882NP_570952CYP4F14MouseCyp4fr1 4NM_022434Q9EP75CYP4F15MouseCyp4fr15NM_134127NP_598888CYP4F16MouseCyp4fr16NM_024442NP_077762CYP4F18MouseCyp4f18NM_024444 Q99N16RatCyp4f18NM _001033686 Q3MID2CYP4F22HumanCYP4F22NM_173483 Q6NT55CYP4F39MouseCyp4f39NM_177307 NP_796281RatCyp4f39XM_234837 XP_234837CYP4V2HumanCYP4V2XM_2 09612Q6ZWL3CYP4V3MouseCyp4v3NM_133969Q9DBW0RatCyp4v3NM_001135600Q9EPX8CYP4X1HumanCYP4X1NM_178033Q8N118MouseCyp4x1NM_001003947NP_001003947RatCyp4x1NM_145675Q8K4D6CYP4Z1HumanCYP 4Z1NM_178134Q86W10CYP5A1HumanTBXAS1NM_001061Q9HD80MouseTbxas1NM_011539P36423CYP7A1HumanCYP7A1NM_000780P22680MouseCyp7a1NM_007824Q64505RatCyp 7a1NM_012942P18125CYP7B1HumanCYP7B1NM_004820O75881MouseCyp7b1NM_007825Q60991RatCyp7b1NM_019138Q63688CYP8A1HumanPTGISNM_000961Q16647MousePtgi sNM_008968O35074RatPtgisNM_031557Q62969CYP8B1HumanCYP8B1NM_004391Q9UNU6MouseCyp8b1NM_010012O88962RatCyp8b1NM_031241Q9WTN7CYP11A1HumanCYP1 1A1NM_000781P05108MouseCyp11a1NM_019779Q9QZ82RatCyp11a1NM_017286P14137CYP11B1HumanCYP11B1NM_001026213P15538MouseCyp11b1NM_001033229NP_ 001028401RatCyp11b1NM_012537P15393CYP11B2HumanCYP11B2NM_000498P19099MouseCyp11b2NM_009991P15539RatCyp11b2NM_012538P30099CYP17A1HumanCY P17A1NM_000102P05093MouseCYP17A1NM_007809P27786RatCyp17a1NM_012753Q6LCX9CYP19A1HumanCYP19A1NM_031226P11511MouseCyp19a1NM_007810P28649R atCyp19a1NM_017085P22443CYP20A1HumanCYP20A1NM_020674Q6UW02MouseCyp20a1NM_030013Q8BKE6RatCyp20a1NM_199401Q6P7D4CYP21A1MouseCyp21a1NM_009995P03940RatCyp21a1NM_057101Q8R402CYP21A 2HumanCYP21A2NM_000500P08686CYP24A1HumanCYP24A1NM_001128915Q07973MouseCyp24a1NM_009996Q64441RatCyp24a1NM_201635Q09128CYP26A1HumanCYP26A1 NM_057157O43174MouseCyp26a1NM_007811O55127RatCyp26a1NM_130408Q304P5CYP26B1HumanCYP26B1NM_019885Q9NR63MouseCyp26b1NM_175475NP_780684RatCy p26b1NM_181087Q80YE5CYP26C1HumanCyp26c1NM_183374Q6V0L0MouseCyp26c1NM_001105201NP_001098671RatCyp26c1XM_217935XP_217935CYP27A1HumanCYP2 7A1NM_000784Q02318MouseCyp27a1NM_024264Q9DBG1RatCyp27a1NM_178847P17178CYP27B1HumanCYP27B1NM_000785O15528MouseCyp27b1NM_010009O35084RatC yp27b1NM_053763O35132CYP27C1HumanCYP27C1NM_001001665Q4G0S4CYP39A1HumanCYP39A1NM_016593Q9NYL5MouseCyp39a1NM_018887Q9JKJ9RatCyp39a1NM_00 1106893XP_236983CYP46A1HumanCYP46A1NM_006668Q9Y6A2MouseCyp46a1NM_010010Q9WVK8RatCyp46a1NM_001108723XP_343109CYP51A1HumanCYP51A1NM_000 786Q16850MouseCyp51NM_020010NP_064394RatCyp51NM_012941Q64654Fea新产品7645 | FHT 2344强效 SMARCA2/4 抑制剂7892 |用于标记突变体 FKBP12F36V 蛋白的 dTAG-荧光素荧光探针7368 | Cell Counting Kit-8细胞活力及增殖检测试液7842 | NAMPT PROTAC® A7强效选择性烟酰胺磷酸核糖转移酶降解剂7898 | ZZL 7 SERT 和 nNOS 之间相互作用的抑制剂我们如何帮助您？
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