Description: Induces cardiomyocyte differentiation in ESCs Chemical Name: 4-(2-Hydroxyethylamino)-2-(4-methoxyphenylamino)-pyrimidine hydrochloride Purity: ≥98% (HPLC) Biological Activity Technical Data Solubility Calculators DatasheetsReferences

Biological Activity

Induces differentiation of mouse embryonic stem cells (ESCs) into cardiomyocytes (EC₅₀ = 100 nM).

Compound Libraries

Cardiogenol C hydrochloride is also offered as part of the Tocriscreen Plus and Tocriscreen Stem Cell Toolbox. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt	296.75
Formula	C13H16N4O2.HCl
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1049741-55-0
PubChem ID	16078958
InChI Key	QQAHYSZVJLHCNA-UHFFFAOYSA-N
Smiles	OCCNC1=CC=NC(NC2=CC=C(OC)C=C2)=N1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM Solubility

DMSO	29.68	100
water	29.68	100

Preparing Stock Solutions

The following data is based on the product molecular weight 296.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg

1 mM	3.37 mL	16.85 mL	33.7 mL
5 mM	0.67 mL	3.37 mL	6.74 mL
10 mM	0.34 mL	1.68 mL	3.37 mL
50 mM	0.07 mL	0.34 mL	0.67 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet Safety Datasheet Select another language: English German French Spanish View SDS

References

References are publications that support the products\' biological activity.

Wu et al (2004) Small molecules that induce cardiomyogenesis in embryonic stem cells. J.Am.Chem.Soc. 126 1590 PMID: 14871063

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Keywords: Cardiogenol C hydrochloride, supplier, induces, mouse, embryonic, stem, cells, ESCs, differentiation, cardiomyocytes, cardiomyogenesis, ESCs, and, iPSC, Cardiomyocyte, Stem, Cells, ESCs, and, iPSC, Tocris Bioscience

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