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Tocris/Nitrocaramiphen hydrochloride/0469/10/10 mg

作者: 时间:2024-09-20 点击量:

Description: Muscarinic antagonist, M1 > M2 Chemical Name: 2-Diethylaminoethyl 1-(4-nitrophenyl)cyclopentanecarboxylate hydrochloride Purity: ≥98% (HPLC) Biological Activity Technical Data Solubility Calculators DatasheetsReferences

Biological Activity

Muscarinic antagonist with 71-fold selectivity for M1 over M2.

Technical Data

M. Wt 370.88
Formula C18H26N2O4.HCl
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 98636-73-8
PubChem ID 25102587
InChI Key XWQWACGTGFICFO-UHFFFAOYSA-N
Smiles O=C(OCCN(CC)CC)C2(CCCC2)C1=CC=C([N+]([O-])=O)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 10 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 370.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.7 mL 13.48 mL 26.96 mL
5 mM 0.54 mL 2.7 mL 5.39 mL
10 mM 0.27 mL 1.35 mL 2.7 mL
50 mM 0.05 mL 0.27 mL 0.54 mL
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Product Datasheets

Certificate of Analysis is currently unavailableon-line. Please contact Customer Service Safety Datasheet Select another language: English German French Spanish View SDS

References

References are publications that support the products\' biological activity.

Hudkins et al (1991) Muscarinic receptor binding. Profile of para-sustituted caramiphen analogues. J.Med.Chem 34 2984 PMID: 1920350

Hudkins et al (1993) Caramiphen, iodocaramiphen and nitrocaramiphen are potent, competitive, muscarine M1 receptor selective agents. Eur.J.Pharmacol. 231 485 PMID: 8449241


Keywords: Nitrocaramiphen hydrochloride, supplier, Muscarinic, antagonists, M1, Receptors, Acetylcholine, ACh, M1, Receptors, M1, Receptors, Tocris Bioscience

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