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Tocris/Ginkgolic Acid/6326/50/50 mg

价格
¥11380.00
货号:6326/50
浏览量:127
品牌:Tocris
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Description:InhibitsSUMOylationbybindingE1
ChemicalName:2-Hydroxy-6-(8Z)-8-pentadecenylbenzoicacid
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofSUMOylation(IC50=3μM).DirectlybindsE1andinhibitsformationofE1-SUMOintermediate.Protectsagainstamyloidβ-inducedimpairmentofneurotransmissionandsynapticplasticity.AlsosuppressesCD44andMMP14expressioninbreastcancercells,eliminatingcancerstemcellsandinhibitingtumOrigenesis.

TechnicalData

M.Wt346.5
FormulaC22H34O3
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber22910-60-7
PubChemID5281858
InChIKeyYXHVCZZLWZYHSA-FPLPWBNLSA-N
SmilesCCCCCC/C=CCCCCCCCC1=C(C(O)=CC=C1)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.65100
ethanol34.65100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight346.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.89mL14.43mL28.86mL
5mM0.58mL2.89mL5.77mL
10mM0.29mL1.44mL2.89mL
50mM0.06mL0.29mL0.58mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet