Bpsbioscience/RSK3, GSTtag/40182/10 µg相关交流-蚂蚁淘在线

Bpsbioscience/RSK3, GSTtag/40182/10 µg

苏州蚂蚁淘 /发布时间:1630519202 /浏览量:19

Species:Human

HostSpecies:Sf9insectcells

MW:112kDa

Genbank#:NM_021135

Tag(s):N-terminalGST-tag

a.a:fulllength

Background:

RSK3isamemberoftheRSK(ribosomalS6kinase)familythatencodesa733-amino-acidproteinwithauniqueN-terminalregioncontainingaputativenuclearlocalizationsignal(1).RSK3mRNAiswidelyexpressedandisactivatedbygrowthfactors,serumandphorbolester.Uponstimulation,RSK3translocatestothecellnucleusandphosphorylatesnuclearproteins.RSK3canbindtoERK1/2andthisassociationincreasesthedurationofRSK3activation(2).

Description:

RecombinanthumanRSK3(ribosomalS6kinase3),fulllength,withN-terminalGST-tag,expressedbySf9insectcellsviaabaculovirusexpressionsystem.

Synonym(s):

RSK;HU-2;RSK3;p90-RSK3;pp90RSK3;MAPKAPK1C;S6K-alpha;S6K-alpha2

Purity:

≥75%

Formulation:

50mMTris-HCl,pH7.5,150mMNaCl,0.25mMDTT,0.1mMEGTA,0.1mMEDTA,0.1mMPMSF,25%glycerol.

Format:

Aqueousbuffersolution

Storage/Stability:

>6monthsat-80°C.

Application(s):

Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.

Reference(s):

1.Zhao,Y.etal:RSK3encodesanovelpp90rskisoformwithauniqueN-terminalsequence:growthfactor-stimulatedkinasefunctionandnucleartranslocation.MolCellBiol.1995Aug;15(8):4353-63.
2.Roux,PP.etal:Phosphorylationofp90ribosomalS6kinase(RSK)regulatesextracellularsignal-regulatedkinasedockingandRSKactivity.MolCellBiol.2003Jul;23(14):4796-804.

Warning(s):

Avoidfreeze/thawcycles

ScientificCategory:

Kinase/Serine-Threonine

ProductType:

RecombinantProtein

Datashownislot-specific.Contactusforspecificinformationonotherlots.

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