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商品描述
β-Glycyrrhetinic acid
Product Code:
9586-1G
Pack Size:
1 g
Form:
Biochemicals
Applications:
Enzyme Inhibition
Shipping Temp:
gel pack
Storage Temp:
-20°C
Product Type:
Biochemical
Description:
β-Glycyrrhetinic acid is a major metabolite of glycyrrhizin, one of the main constituents of licorice. It inhibits 15-PGDH (15-hydroxyprostaglandin dehydrogenase) leading to increased prostaglandin concentration in the digestive system. Displays anti-ulcerative, anti-inflammatory, and immunomodulatory properties. In addition, β-Glycyrrhetinic acid inhibits mammalian DNA polymerases α, γ, κ, and λ with IC???values of 16.1, 19.3, 15.8, and 13.7 μM, respectively. Also protects liver against the toxic effect of chemotherapeutic alkylating agents via activation of Nrf2 (NF-E2-related factor-2)?and PPARγ.
Supplier:
BioVision
Product Category:
Signalling Pathways - Small Molecules > Inhibitors
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Product Code:
9586-1G Price (1 g):
£114.00 excluding VATDiscount available for 2 or more products. Visit Special Offers page for details.
