品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
蚂蚁淘在线 / 品牌中心 / Hycult Biotech / Hycult Biotech/Monocytes/Macrophages, Mouse, mAb ER-HR3/HM1088/100 µg
商品描述
Description:Monocytes/Macrophages,Mouse,mAbER-HR3
ThemonoclonalantibodyER-HR3isreactivetothemajorityofmousemonocytesandasubsetofmatureresidentmacrophages,especiallythoselocatedinhemopoieticorgans.WhereasallotherleukocytesareER-HR3negative,upto70%ofcirculatingmonocytesstainpositivewiththismonoclonalantibody.FurThermore,about30%ofbonemarrowcellsexpresstheantigen.OtherER-HR3positivemacrophagescanbefoundinthesplenicredpulp,inthemesentericlymphoidparacortex,interfollicularareasofPeyer"spatchesandbonemarrow.FewER-HR3positivecellsareobservedinthethymiccortexandtheconnectivetissuesofthegastro-intestinaltract,thedermisandtherenalmedulla.EpidermalLangerhanscellsalsoexpresstheantigen.ThemonoclonalantibodyER-HR3canbeusedtoidentifyandlocalizeaverydistinctmaturetissuemacrophagesubpopulationfoundinvariousmouseorgansanditsdistributionpatternisuniquecomparedtothatfromothermacrophage-specificantibodies.TheantibodyisespeciallysuitableforontogenicstudiesbecauseER-HR3positivemacrophagesarecloselyrelatedtohemopoieticislands,especiallyaterythropoieticsites.
Specifications:
Catalognumber | HM1088 |
---|---|
Producttype | Monoclonalantibodies |
Quantity | 100µg |
Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
Application | Flowcytometry,Frozensections,Paraffinsections |
Use | Forflowcytometryandimmunohistologydilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
Isotype | RatIgG2c |
Species | Mouse |
References | 1.deJong,Jetal;Amonoclonalantibody(ER-HR3)againstmurinemacrophages.I.Ontogeny,distributionandenzymehistochemicalcharacterizationofER-HR3-positivecells.CellTissueRes1994,275:5672.deJong,Jetal;Amonoclonalantibody(ER-HR3)againstmurinemacrophages.II.BiochemicalandfunctionalaspectsoftheER-HR3antigen.CellTissueRes1994,275:577 |
StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
Disease | Infectiousdiseases |