Chloramphenicol succinate sodium is the salt prepared from chloramphenicol succinate using the free carboxylic acid of the succinate which ionises and readily forms in weak sodium hydroxide solutions. The sodium salt is the preferred formulation for pharmaceutical applications, providing a more readily soluble product. Chloramphenicol succinate is significantly less active than chloramphenicol but acts as a prodrug, forming chloramphenicol in the presence of succinate dehydrogenase.

Chloramphenicol succinate sodium is soluble in ethanol, methanol, DMF and DMSO. 

CAS Number

982-57-0

Molecular Formula

C₁₅H₁₅Cl₂N₂O₈Na

Molecular Weight

445.2

Mechanism of Action

After entering a bacterial cell, chloramphenicol binds to the 50S ribosomal subunit preventing peptide bond formation. Resistance to chloramphenicol may be due to decreased cell permeability or a mutation in the 50S ribosomal subunit.

Storage Conditions

-20°C

Specifications:

TOKU-E植物生物学植物生物学，基因工程，改变植物生长特性。植物生物学是指植物的科学和研究。植物的特性和生长可以通过多种方式进行改变，包括基因工程和各种生长调节剂或激素的使用。可以通过农杆菌介导的转化或其他方法将DNA导入植物，  其中将质粒上的目标基因从农杆菌  细胞中转移  并整合到植物组织中。植物还易受细菌和真菌性植物病原体的侵害，而使用低毒性抗生素  和  抗真菌药可以控制或消除这些病原体  。